Biochemistry of Ataxia

Biochemistry of cardiomyopathy in the mitochondrial disease Friedreich's ataxia.

FRDA (Friedreich's ataxia) is a debilitating mitochondrial disorder leading to neural and cardiac degeneration, which is caused by a mutation in the frataxin gene that leads to decreased frataxin expression. The most common cause of death in FRDA patients is heart failure, although it is not known how the deficiency in frataxin potentiates the observed cardiomyopathy. The major proposed biochem...

The 15th Iranian National Congress of Biochemistry & 6th International Congress of Biochemistry and Molecular Biology

A Case Study of Ataxia Teilangiectasia Associated with Hodgkin Diease

A case of ataxia telangiectasia in a 7 year-old boy associated with Hodgkin disease was presented. Abnormalities of motion along with repeated respiratory tract infections requiring hospitalization started when he was 2 years old. The patient was placed on MOPP protocol Hodgkin treatment in addition to replace­ment therapy as advised. 

Editor Note – Biochemistry & Analytical Biochemistry

Biochemistry is the study of structures, functions and interactions of biomolecules, such as carbohydrates, nucleic acids, proteins, lipids, etc. and their metabolisms. Advancements in biochemistry helps in the advancement of different fields like agriculture, medicine, nutrition, etc., which are directly related to it. Combination of biochemical techniques with techniques and ideas of genetics...

Update on Biochemistry of Plant Volatiles Biochemistry of Plant Volatiles

Plants have a penchant for perfuming the atmosphere around them. Since antiquity it has been known that both floral and vegetative parts of many species emit substances with distinctive smells. The discovery of the gaseous hormone ethylene 70 years ago brought the realization that at least some of the compounds emitted may have physiological significance without any distinctive smell to humans....